Introduction: The notion of restorative dentistry has undergone significant development as a result of the usage of computer-aided design and computer-aided manufacturing (CAD-CAM) in the dental industry.

Methodology: Two 3D-printed acrylic resins and one heat-polymerized resin (HP) were used to design and create 480 rectangular samples, each measuring 64103.3 mm. Three sets of 3D-printed objects were created using different printing orientations (0, 45, and 90 degrees), and each group was then separated into four separate sets using different postcuring times (30, 60, 90, and 120 minutes). Prior flexural strength testing, all specimens underwent 10,000 cycles of thermal cycling. Scanning electron microscopes (SEM) were used to investigate fractured surfaces. Statistical evaluation was done using ANOVA and Tukey's post hoc tests (p 0.05).

Results: The findings of this investigation demonstrated that 0-degree groups had the highest flexural strength values of 3D-printed resin. (Additionally, despite of the printing orientation, the values for flexural strength rose as postcuring time extended; the highest flexural strength was noted at 120 minutes postcuring time in all orientations. It was confirmed by SEM research that a ductile fracture had a coarser surfaces and irregular lamellae, and that these characteristics become noticeably more pronounced with longer postcuring times. In light of the findings.