Aim: Aim of this in vitro study was to compare and evaluate the compressive strength of Conventional GIC and two different concentrations of Nanocurcumin incorporated GIC.

Materials & Method: A total of 45 specimen blocks (3x6mm) was prepared for this study.

The specimen were divided into 3 groups consisting of 15 samples each. Group A consisting of (n=15) samples of Conventional GIC (Control group), Group B consisting of 15 samples of 80/20% of Nanocurcumin incorporated GIC & Group C consisting of 70/30% of Nanocurcumin incorporated GIC. The specimen were immersed in water for 24hrs at 37^oC to mimic the oral environment. The samples were then tested for compressive strength using Universal Testing Machine.

Compressive load was applied along the long axis of the specimen, at a cross-head speed of (0.75 ± 0.30) mm min⁻¹_, using a Universal testing machine with load cell of 1000 N.

Results: Group C (70/30% wt Nanocurmin incorporated GIC) had the highest compressive strength followed by Group B (80/20% wt Nanocurcumin incorporated GIC) and Group A (control group) had the least compressive strength.